Chemical Biology, Organic Synthesis, Medicinal Chemistry
We just published the first total syntheses of several bis-b-carboline alkaloids, picrasidines G, S, R, and T, and natural product-like derivatives in a divergent manner. The work was recently published on Chemical Science.
Divergent total syntheses of ITHQ-type bis-bcarboline alkaloids by regio-selective formal aza-[4 + 2] cycloaddition and late-stage C–H functionalization.