Yun-Nian, Rui-Qi, Dong-Chen and Qing’s work on highly chemoselective synthesis of hindered amides enabled by cobalt-catalyzed intermolecular oxidative hydroamidation has been published on Nature Communications.
In the presence of CoSalen, oxone and silane, bulky α-tertiary amides were efficiently accessed from unactivated alkenes and nitriles of either solvent- or reagent quantities.
