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2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | Pre-PKU

 

2024

  1. Zhang F.; Cheng Y.; Xue B.; Gao Y.; Liu, Y.; Wang, C. MetalNet2: an enhanced server for predicting metal-binding sites in proteomes. National Science Review 2024, nwae391.
  1. Zhang, J.; Gao, Z.; Xiao, W.; Jin, N.; Zeng, J.; Wang, F.; Jin, X.; Dong, L.; Lin, J.; Gu, J.; Wang, C. A simplified and efficient extracellular vesicle-based proteomics strategy for early diagnosis of colorectal cancer. Chemical Science 2024, 15(44), 18419-18430.
  1. Liu, Z.; Liu, D.; Wang, C. In situ chemoproteomic profiling reveals itaconate inhibits de novo purine biosynthesis in pathogens. Cell Rep. 2024, 43(9), 114737.
  1. Li, X.; Zhang, J.; Xiao, Y.; Song, H.; Li, Y.; Li, W.; Cao, R.; Li, S.; Qin, Y.; Wang, C.; Zhong, W. Chemoproteomics enables identification of coatomer subunit zeta-1 targeted by a small molecule for enterovirus A71 inhibition. MedComm. 2024, 5 (6), e587.
  1. Wei, C.; Xiao, Z.; Zhang, Y.; Luo, Z.; Liu, D.; Hu, L.; Shen, D.; Liu, M.; Shi, L.; Wang, X.; Lan, T.; Dai, Q.; Liu, J.; Chen, W.; Zhang, Y.; Sun, Q.; Wu, W.; Wang, P.; Zhang, C.; Hu, J.; Wang, C.; Yang, F.; Li, Q. Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke. Cell Death Differ. 2024, 31 (8), 983-998.
  1. Zeng, X.; Wei, T.; Wang, X.; Liu, Y.; Tan, Z.; Zhang, Y.; Feng, T.; Cheng, Y.; Wang, F.; Ma, B.; Qin, W.; Gao, C.; Xiao, J.; Wang, C. Discovery of metal-binding proteins by thermal proteome profiling. Nat. Chem. Biol. 2024, 20 (6), 770-778.
  1. Li, Z.; Liu, D.; Wang, Y.; Wang, C. Chemoproteomic Profiling of Erastin-Interacting Proteins. Chem. Res. Toxicol. 2024, 37 (1), 109-116.
  1. He, T.-B.; Yan, B.-C.; Zhou, Y.-F.; Sang, Y.-Q.; Li, X.-N.; Sun, H.-D.; Wang, C.; Xue, X.-S.; Puno, P.-T. Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4 + 2] cycloaddition and target differentiation of enantiomers. Chem. Sci. 2024, 15 (4), 1260-1270.

2023

  1. Zhu, Y.; Wang, L.; Li, J.; Zhao, Y.; Yu, X.; Liu, P.; Deng, X.; Liu, J.; Yang, F.; Zhang, Y.; Yu, J.; Lai, L.; Wang, C.; Li, Z.; Wang, L.; Luo, T. Photoaffinity labeling coupled with proteomics identify PDI-ADAM17 module is targeted by (-)-vinigrol to induce TNFR1 shedding and ameliorate rheumatoid arthritis in mice. Cell Chem Biol 2023
  1. Xiao, W.; Chen, Y.; Zhang, J.; Guo, Z.; Hu, Y.; Yang, F.; Wang, C. A Simplified and Ultrafast Pipeline for Site-Specific Quantitative Chemical Proteomics. J. Proteome Res. 2023, 22 (10), 3360-3367.
  1. Wang, X.; Zhang, Y.; Wang, C. Discovery of cisplatin-binding proteins by competitive cysteinome profiling. RSC Chem. Biol. 2023, 4 (9), 670-674.
  1. Liu, D.; Xiao, W.; Li, H.; Zhang, Y.; Yuan, S.; Li, C.; Dong, S.*; Wang, C.*; Discovery of Itaconate-Mediated Lysine Acylation. J. Am. Chem. Soc. 2023, 145 (23), 12673-12681.
  1. Wang, Q.; Wang, F.; Li, R.; Wang, P.; Yuan, R.; Liu, D.; Liu, Y.; Luan, Y.*; Wang, C.*; Dong, S.* Fine Tuning the Properties of Stapled Peptides by Stereogenic α‐Amino Acid Bridges. Chem. Eur. J. 2023, e202203624.
  1. Gao, J.; Sheng, X.; Du, J.; Zhang, D.; Han, C.; Chen, Y.; Wang, C.*; Zhao, Y.* Identification of 113 new histone marks by CHiMA, a tailored database search strategy. Sci. Adv. 2023, 9 (14), eadf1416.
  1. Xiao, W.; Chen, Y.; Wang, C.* Quantitative Chemoproteomic Methods for Reactive Cysteinome Profiling. Isr. J. Chem. 2023, e202200100.
  1. Cheng, Y.; Wang, H.; Xu, H.; Liu, Y.*; Ma, B.; Chen, X.; Zeng, X.; Wang, X.; Wang, B.; Shiau, C.; Ovchinnikov, S.; Su, X.-D.*; Wang, C.* Co-evolution-based prediction of metal-binding sites in proteomes by machine learning. Nat. Chem. Biol. 2023, 19 (5), 548-555.

 

2022

  1. Chen, Y.; Quan, B.; Li, Y.; Liu, Y.; Qin, W.; Wang, C.* Quantitative profiling of PTM stoichiometry by resolvable mass tags. RSC Chem. Biol. 2022, 3 (11), 1320-1324.
  1. Wang, Y.; Wang, C.* Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation. Cell Death Differ. 2022, 30, 125-136.
  1. Chen, Y.; Wang, C.*, Profiling of Protein Carbonylations in Ferroptosis by Chemical Proteomics. Methods Mol. Biol. 2022, 2543, 141-153.
  1. Yang, F.; Wang, C.*, Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2022.
  1. Liu, B.; Zhuang, S.; Tian, R.; Liu, Y.; Wang, Y.; Lei, X.*; Wang, C.*, Chemoproteomic Profiling Reveals the Mechanism of Bile Acid Tolerance in Bacteria. ACS Chem. Biol. 2022, 17 (9), 2461-2470.
  1. Chen, X.; Liu, Y.; Kong, L.; Wen, Z.; Wang, W.; Wang, C.*, Quantitative Chemoproteomic Profiling of Protein Cross-Links Induced by Methylglyoxal ACS Chem. Biol. 2022, 17 (8), 2010-2017.
  1. Tang, H.; Jia, G.; Gao, J.; Yang, F.; Tang, Z.; Liu, Y.; Wang, C.*, Quantifying Turnover Dynamics of Selenoproteome by Isotopic Perturbation. Anal. Chem. 2022, 94 (27), 9636-9647.
  1. Yang, F.; Chen, N.; Wang, F.; Jia, G.; Wang, C.*, Comparative reactivity profiling of cysteine-specific probes by chemoproteomics. Current Research in Chemical Biology 2022, 2, 100024.
  1. Lai, S.; Chen, Y.; Yang, F.; Xiao, W.; Liu, Y.; Wang, C.*, Quantitative site-specific chemoproteomic profiling of protein lipoylation. J. Am. Chem. Soc. 2022, 144 (23), 10320-10329.
  1. Xie, B.; Pu, Y.; Yang, F.; Chen, W.; Yue, W.; Ma, J.; Zhang, N.; Jiang, Y.; Wu, J.; Lin, Y.; Liang, X.; Wang, C.; Zou, P.; Li, M., Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification. Cancer Res. 2022, 82 (14), 2576-2592.
  1. Runtsch, M. C.; Angiari, S.; Hooftman, A.; Wadhwa, R.; Zhang, Y.; Zheng, Y.; Spina, J. S.; Ruzek, M. C.; Argiriadi, M. A.; McGettrick, A. F.; Mendez, R. S.; Zotta, A.; Peace, C. G.; Walsh, A.; Chirillo, R.; Hams, E.; Fallon, P. G.; Jayaraman, R.; Dua, K.; Brown, A. C.; Kim, R. Y.; Horvat, J. C.; Hansbro, P. M.; Wang, C.; O’Neil, L. A. J.*, Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages. Cell Metab. 2022, 34 (3), 487-501
  1. Yang, F.; Jia, G.; Guo, J.; Liu, Y.; Wang, C.*, Quantitative Chemoproteomic Profiling with Data-Independent Acquisition-Based Mass Spectrometry. J. Am. Chem. Soc. 2022, 144 (2), 901-911
  1. Chen, Y.#; Qin, W.#; Wang, C.*, Functional Proteomics Driven by Chemical and Computational Approaches. Chin. J. Chem. 2022, 40, 628-634
  1. Jia, G.; Gao, J.; Yang, F.; Feng, T.; Wang, C.*, An accelerated and optimized algorithm of selenium-encoded isotopic signature targeted profiling for global selenoproteome analysis. Methods Enzymol. 2022, 662, 241-258
  1. Cui, J.#; Zhao, Q.#; Song, Z.; Chen, Z.; Zeng, X.; Wang, C.; Lin, Z.; Wang, F.; Yang, Y.*, KLHL24-mediated hair follicle stem cells structural disruption causes alopecia. J. Invest. Dermatol. 2022 Jan 20: S0022-202X(22)00016-1

 

2021

  1. Gao, J.#; Liu, Y.#; Yang, F.; Chen, X.; Cravatt, B. F.; Wang, C.*, CIMAGE2.0: An Expanded Tool for Quantitative Analysis of Activity-Based Protein Profiling (ABPP) Data. J. Proteome Res. 2021, 20, 10, 4893–4900
  1. Zeng, X.#; Cheng, Y.#; Wang, C.*, Global Mapping of Metalloproteomes. Biochemistry. 2021, 60, 46, 3507–3514
  1. Wang, J.#; Liu, Y.#; Liu, Y.#; Wang, C.*; Chen, P. R.*, CAGE-prox: A Unified Approach for Time-Resolved Protein Activation in Living Systems. Curr Protoc. 2021 Jun;1(6): e180
  1. Zhang, Y.; Qin, W.; Liu, D.; Liu, Y.; Wang, C.*, Chemoproteomic profiling of itaconations in Salmonella. Chem. Sci. 2021, 12, 6059
  1. Dubiella, C.#; Pinch, B.J.#; Koikawa, K.; Zaidman, D.; Poon, E.; Manz, T. D.; Nabet, B.; He, S.; Resnick, E.; Rogel, A.; Langer, E. M.; Daniel, C. J.; Seo, H.; Chen, Y.; Adelmant, G.; Sharifzadeh, S.; Ficarro, S. B.; Jamin, Y.; Costa, B. M.; Zimmerman, M. W.; Lian, X.; Kibe, S.; Kozono, S.; Doctor, Z. M.; Browne, C. M.; Yang, A.; Barak, L. S.; Shah, R. B.; Vangos, N. E.; Geffken, E. A.; Oren, R.; Koide, E.; Sidi, S.; Shulman, Z., Wang, C.; Marto, J. A.; Paganon, S. D.; Look, T.; Zhou, Z.; Lu, K.; Sears, R. C.; Chesler, L.; Gray, N. S.; London, N., Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat. Chem. Biol. 2021. 17, 954–963
  1. Chen, C.#; Chen, Y.#; Lu, J.#; Chen, Z.; Wang, C.*; Pi, R.*, Acrolein-conjugated proteomics in brains of adult C57BL/6 mice chronically exposed to acrolein and aged APP/PS1 transgenic AD mice. Toxicol. Lett. 2021, 344, 11-17
  1. Huang, Y.; Li, Z.; Zhang, L.; Tang, H.; Zhang, H.; Wang, C.; Chen, S. Y.; Bu, D.; Zhang, Z.; Zhu, Z.; Yuan, P.; Li, K.; Kong, W.; Tang, C.; Jung, Y.; Ferreira, R. B.; Carroll, K. S.; Du, J.; Yang, J.; Jin, H.*, Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling, Redox Biol. 2021, 41, 101898.
  1. Liu, J.#; Shao, X.#; Qin, W.#; Zhang, Y.#; Dang, F.; Yang, Q.; Yu, X.; Li, Y.; Chen, X.; Wang, C.*; Wang, Y., Quantitative Chemoproteomics Reveals O-GlcNAcylation of Cystathionine γ-lyase(CSE) Represses Trophoblast Syncytialization. Cell Chem. Biol. 2021, 28 (6), 788-801
  1. Pan, M.#; Zheng, Q.#; Yu, Y.#; Ai, H.; Xie, Y.; Zeng, X.; Wang, C.; Liu, L.; Zhao, M.; Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun. 2021, 12 (1):121.
  1. Chen, N.; Wang, C.*, Chemical Labeling of Protein 4’-Phosphopantetheinylation. Chembiochem 2021, 22 (8), 1357-1367.
  1. Zhang, Y.; Qin, W.; Wang, C.*, Discovery of post-translational modifications in immunometabolism by chemical proteomics. Curr. Opin. Biotech. 2021. 68, 37-43

 

2020

  1. Wang, X.; Wang, H.; Xu, B.; Huang, D.; Nie, C.; Pu, L.; Zajac, G. J. M.; Yan, H.; Zhao, J.; Shi, F.; Emmer, B. T.; Lu, J.; Wang, R.; Dong, X.; Dai, J.; Zhou, W.; Wang, C.; Gao, G.; Wang, Y.; Willer, C.; Lu, X.; Zhu, Y.; Chen, X.-W.*, Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans. Cell Metab. 2020.
  1. Yang, F.; Wang, C.*, Profiling of post-translational modifications by chemical and computational proteomics. Chem Comm 2020. 56 (88), 13506-13519.
  1. Ye, Z.#; Wang, Y.#; Wu, H.#; Song, T.; Li, X.; Liu, Q.*; Wang, C.*, Chemoproteomic Profiling of an Ibrutinib Analogue Reveals its Unexpected Role in DNA Damage Repair. Chembiochem 2020.
  1. Yin, H. Y.#; Gao, J. J.#; Chen, X. M.#; Ma, B.#; Yang, Z. S.; Tang, J.; Wang, B. W.; Chen, T. F.; Wang, C.*; Gao, S.; Zhang, J. L., A Gallium(III) Complex that Engages Protein Disulfide Isomerase A3 (PDIA3) as an Anticancer Target. Angew. Chem. Int. Ed. Engl. 2020, 59 (45), 20147-20153.
  1. Chen, N.; Liu, Y.; Li, Y.; Wang, C.*, Chemical Proteomic Profiling of Protein 4’-Phosphopantetheinylation in Mammalian Cells. Angew. Chem. Int. Ed. Engl. 2020, 59 (37), 16069-16075.
  1. Qin, W.#; Zhang, Y.#; Tang, H.; Liu, D.; Chen, Y.; Liu, Y.; Wang, C.*, Chemoproteomic Profiling of Itaconation by Bioorthogonal Probes in Inflammatory Macrophages. J Am Chem Soc 2020, 142 (25), 10894-10898.
  1. Qin, W.; Yang, F.; Wang, C.*, Chemoproteomic profiling of protein-metabolite interactions. Curr Opin Chem Biol 2020, 54, 28-36.

 

2019

  1. Chen, Y.; Qin, W.; Li, Z.; Guo, Z.; Liu, Y.; Lan, T.; Wang, C.*, Site-specific chemoproteomic profiling of targets of glyoxal. Future medicinal chemistry 2019, 11 (23), 2979-2987.
  1. Qin, W.; Xie, Z.; Wang, J.; Ou, G.; Wang, C.*; Chen, X.*, Chemoproteomic profiling of O-GlcNAcylation in caenorhabditis elegans. Biochemistry 2019, 59 (34), 3129–3134.
  1. Qin, W.; Qin, K.; Zhang, Y.; Jia, W.; Chen, Y.; Cheng, B.; Peng, L.; Chen, N.; Liu, Y.; Zhou, W.; Wang, Y. L.; Chen, X.*; Wang, C.*, S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate. Nat. Chem. Biol. 2019, 15 (10), 983-991.
  1. Liu, F.; Wang, H.; Li, S.; Bare, G. A. L.; Chen, X.; Wang, C.; Moses, J. E.; Wu, P.; Sharpless, K. B., Biocompatible SuFEx click chemistry: thionyl tetrafluoride (SOF4)-derived connective hubs for bioconjugation to DNA and proteins. Angew. Chem. Int. Ed. Engl. 2019, 58 (24), 8029-8033.
  1. Resnick, E.; Bradley, A.; Gan, J.; Douangamath, A.; Krojer, T.; Sethi, R.; Geurink, P. P.; Aimon, A.; Amitai, G.; Bellini, D.; Bennett, J.; Fairhead, M.; Fedorov, O.; Gabizon, R.; Gan, J.; Guo, J.; Plotnikov, A.; Reznik, N.; Ruda, G. F.; Diaz-Saez, L.; Straub, V. M.; Szommer, T.; Velupillai, S.; Zaidman, D.; Zhang, Y.; Coker, A. R.; Dowson, C. G.; Barr, H. M.; Wang, C.; Huber, K. V. M.; Brennan, P. E.; Ovaa, H.; von Delft, F.; London, N.*, Rapid covalent-probe discovery by electrophile-fragment screening. J. Am. Chem. Soc. 2019, 141 (22), 8951-8968.
  1. Wang, J.#; Liu, Y.#; Liu, Y.#; Zheng, S.; Wang, X.; Zhao, J.; Yang, F.; Zhang, G.; Wang, C.*; Chen, P. R.*, Time-resolved protein activation by proximal decaging in living systems. Nature 2019, 569 (7757), 509-513.
  1. Chen, N.#; Qiao, Z.#; Wang, C.*, A chemoselective reaction between protein N-homocysteinylation and azides catalyzed by heme(ii). Chem. Commun. (Camb.) 2019, 55 (25), 3654-3657.
  1. Chen, Y.; Liu, Y.; Hou, X.; Ye, Z.; Wang, C.*, Quantitative and site-specific chemoproteomic profiling of targets of acrolein Chem. Res. Toxicol. 2019, 32 (3), 467-473

 

2018

  1. Tang, H.#; Dai, Z.#; Qin, X.; Cai, W.; Hu, L.; Huang, Y.; Cao, W.; Yang, F.; Wang, C.; Liu, T.*, Proteomic Identification of Protein Tyrosine Phosphatase and Substrate Interactions in Living Mammalian Cells by Genetic Encoding of Irreversible Enzyme Inhibitors. J. Am. Chem. Soc. 2018, 140 (41), 13253-13259.
  1. Chen, Z.#; Jiang, Z.#; Chen, N.#; Shi, Q.; Tong, L.; Kong, F.; Cheng, X.; Chen, H.; Wang, C.*; Tang, B.*, Target discovery of ebselen with a biotinylated probe. Chem. Commun. (Camb.) 2018, 54 (68), 9506-9509.
  1. Qin, K.#; Zhu, Y.#; Qin, W.; Gao, J.; Shao, X.; Wang, Y.-L.; Zhou, W.; Wang, C.*; Chen, X., Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker. ACS Chem. Biol. 2018, 13 (8), 1983-1989.
  1. Gao, J.#; Yang, F.#; Che, J.; Han, Y.; Wang, Y.; Chen, N.; Bak, D. W.; Lai, S.; Xie, X.; Weerapana, E.; Wang, C.*, Selenium-Encoded Isotopic Signature Targeted Profiling. ACS Cent Sci 2018, 4 (8), 960-970.
  1. Yang, F.#; Gao, J.#; Che, J.; Jia, G.; Wang, C.*, A Dimethyl-Labeling-Based Strategy for Site-Specifically Quantitative Chemical Proteomics. Anal. Chem. 2018, 90 (15), 9576-9582.
  1. Bak, D. W.; Gao, J.; Wang, C.; Weerapana, E., A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome. Cell Chem Biol 2018, 25 (9), 1157-1167 e4.
  1. Liang, K.#; Li, N.#; Wang, X.; Dai, J.; Liu, P.; Wang, C.; Chen, X.-W.; Gao, N.; Xiao, J., Cryo-EM structure of human mitochondrial trifunctional protein. Proc. Natl. Acad. Sci. U. S. A. 2018, 115 (27), 7039-7044.
  1. Ye, Z.#; Zhang, X.#; Zhu, Y.; Song, T.; Chen, X.; Lei, X.*; Wang, C.*, Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol. Pharm. 2018, 15 (6), 2413-2422.
  1. Dai, J.; Liang, K.; Zhao, S.; Jia, W.; Liu, Y.; Wu, H.; Lv, J.; Cao, C.; Chen, T.; Zhuang, S.; Hou, X.; Zhou, S.; Zhang, X.; Chen, X.-W.; Huang, Y.; Xiao, R.-P.; Wang, Y.-L.; Luo, T.; Xiao, J.; Wang, C.*, Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis. Proc. Natl. Acad. Sci. U. S. A. 2018, 115 (26), E5896-E5905.
  1. Chen, Y.; Liu, Y.; Lan, T.; Qin, W.; Zhu, Y.; Qin, K.; Gao, J.; Wang, H.; Hou, X.; Chen, N.; Friedmann Angeli, J. P.; Conrad, M.; Wang, C.*, Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe. J. Am. Chem. Soc. 2018, 140, 13, 4712-4720. (This paper was selected as ACS Editor’s Choice and JACS Spotlights)
  1. Chen, N.; Liu, J.; Qiao, Z.; Liu, Y.; Yang, Y.; Jiang, C.; Wang, X.; Wang, C.*, Chemical proteomic profiling of protein N-homocysteinylation with a thioester probe. Chem. Sci., 2018, 9, 2826-2830.
  1. Qin, W.#; Qin, K.#; Fan, X.; Peng, L.; Hong, W.; Zhu, Y.; Lv, P.; Du, Y.; Huang, R.; Han, M.; Cheng, B.; Liu, Y.; Zhou, W.; Wang, C.* and Chen, X.*, Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosacharides during Metabolic Glycan Labeling. Angew. Chem. Int. Ed. 2018, 57, 7, 1817-1820. (This work was selected as a Back Cover and a Very Important Paper)
  1. Wang, H.#; Chen, X.#; Li, C.#; Liu, Y.; Yang, F.; Wang, C.*,Sequence-Based Prediction of Cysteine Reactivity Using Machine Learning. Biochemistry 2018, 57 (4), 451-460. (This paper was selected as ACS Editor’s Choice)

 

2017

  1. Li, X.#; Xiong, X.#; Zhang, M.#; Wang, K.#; Chen, Y.#; Zhou, J.; Mao, Y.; Lv, J.; Yi, D.; Chen, X. W.; Wang, C.; Qian, S. B.; Yi, C.*, Base-Resolution Mapping Reveals Distinct m1A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Molecular Cell 2017, 68, 1–13.
  1. Qin, W.; Lv, P.; Fan, X.; Quan, B.; Zhu, Y.; Qin, K.; Chen, Y.; Wang, C.*; Chen, X.*, Quantitative time-resolved chemoproteomics reveals that stable O-GlcNAc regulates box C/D snoRNP biogenesis. Proc. Natl. Acad. Sci. U. S. A. 2017, 114 (33), E6749-e6758.
  1. Zhuang, S.#; Li, Q.#; Cai, L.; Wang, C.*; Lei, X.*, Chemoproteomic Profiling of Bile Acid Interacting Proteins. ACS Cent Sci 2017, 3 (5), 501-509.
  1. Chen, Y.; Cong, Y.; Quan, B.; Lan, T.; Chu, X.; Ye, Z.; Hou, X.; Wang, C.*, Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017, 12, 712-718.
  1. Liang, X.; Lv, F.; Wang, B.; Yu, K.; Wu, H.; Qi, Z.; Jiang, Z.; Chen, C.; Wang, A.; Miao, W.; Wang, W.; Hu, Z.; Liu, J.; Liu, X.; Zhao, Z.; Wang, L.; Zhang, S.; Ye, Z.; Wang, C.; Ren, T.; Wang, Y.; Liu, Q., Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl-5-(3,4,5-trimethoxybenzamido)p henyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor. J. Med. Chem. 2017, 60 (5), 1793-1816.

 

2016

  1. Chen, Y. ; Qin, W.; Wang, C.*, Chemoproteomic profiling of protein modifications by lipid-derived electrophiles. Curr. Opin. Chem. Biol. 2016, 30, 37-45.
  1. Yang, Y.; Song, H.; He, D.; Zhang, S.; Dai, S.; Lin, S.; Meng, R.; Wang, C.*; Chen, P. R.*, Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label. Nat. Commun. 2016, 7, 12299.
  1. Zhao, S.; Dai, J.; Hu, M.; Liu, C.; Meng, R.; Liu, X.; Wang, C.; Luo, T.*, Photo-induced coupling reactions of tetrazoles with carboxylic acids in aqueous solution: application in protein labelling. Chem. Commun. (Camb.) 2016, 52 (25), 4702-5.
  1. Wang, A.#; Yan, X. E. #; Wu, H. #; Wang, W. #; Hu, C.; Chen, C.; Zhao, Z.; Zhao, P.; Li, X.; Wang, L.; Wang, B.; Ye, Z.; Wang, J.; Wang, C.; Zhang, W.; Gray, N. S.; Weisberg, E. L.; Chen, L.; Liu, J.; Yun, C. H.; Liu, Q.*, Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation. Oncotarget 2016, 7 (43), 69760-69769.

 

2015

  1. Wu, H.#; Wang, A. #; Zhang, W. #; Wang, B. #; Chen, C. #; Wang, W.; Hu, C.; Ye, Z.; Zhao, Z.; Wang, L.; Li, X.; Yu, K.; Liu, J.; Wu, J.; Yan, X. E.; Zhao, P.; Wang, J.; Wang, C.; Weisberg, E. L.; Gray, N. S.; Yun, C. H.; Liu, J.; Chen, L.; Liu, Q.*, Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells. Oncotarget 2015, 6 (31), 31313-22.
  1. Wang, C.*; Chen, N., Activity-based Protein Profiling. Acta Chim. Sin. 2015, 73 (7), 657-668.

 

2014

  1. Shannon, D. A.; Banerjee, R.; Webster, E. R.; Bak, D. W.; Wang, C.; Weerapana, E.*, Investigating the proteome reactivity and selectivity of aryl halides. J. Am. Chem. Soc. 2014, 136 (9), 3330-3.

 

Pre-PKU(selected publication)

  1. Wang, C.*; Weerapana, E.; Blewett, M. M.; Cravatt, B. F.*, A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles. Nat. Methods 2014, 11 (1), 79-85.
  1. Rajagopalan, S.#; Wang, C.#; Yu, K.; Kuzin, A. P.; Richter, F.; Lew, S.; Miklos, A. E.; Matthews, M. L.; Seetharaman, J.; Su, M.; Hunt, J. F.; Cravatt, B. F.; Baker, D.*, Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat. Chem. Biol. 2014, 10 (5), 386-91.
  1. Dix, M. M.#; Simon, G. M. #; Wang, C.; Okerberg, E.; Patricelli, M. P.; Cravatt, B. F.*, Functional interplay between caspase cleavage and phosphorylation sculpts the apoptotic proteome. Cell 2012, 150 (2), 426-40.
  1. Martin, B. R.; Wang, C.; Adibekian, A.; Tully, S. E.; Cravatt, B. F., Global profiling of dynamic protein palmitoylation. Nat. Methods 2011, 9 (1), 84-9.
  1. Weerapana, E.#; Wang, C.#; Simon, G. M.; Richter, F.; Khare, S.; Dillon, M. B.; Bachovchin, D. A.; Mowen, K.; Baker, D.; Cravatt, B. F.*, Quantitative reactivity profiling predicts functional cysteines in proteomes. Nature 2010, 468 (7325), 790-5.
  1. Wang, C.; Vernon, R.; Lange, O.; Tyka, M.; Baker, D.*, Prediction of structures of zinc-binding proteins through explicit modeling of metal coordination geometry. Protein Sci. 2010, 19 (3), 494-506.
  1. Wang, C.#; Schueler-Furman, O.#; Andre, I.; London, N.; Fleishman, S. J.; Bradley, P.; Qian, B.; Baker, D.*, RosettaDock in CAPRI rounds 6-12. Proteins 2007, 69 (4), 758-63.
  1. Wang, C.; Bradley, P.; Baker, D.*, Protein-protein docking with backbone flexibility. J. Mol. Biol. 2007, 373 (2), 503-19.
  1. Wang, C.#; Schueler-Furman, O.#; Baker, D.*, Improved side-chain modeling for protein-protein docking. Protein Sci. 2005, 14 (5), 1328-39.
  1. Schueler-Furman, O.#; Wang, C.#; Baker, D.*, Progress in protein-protein docking: atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side-chain flexibility. Proteins 2005, 60 (2), 187-94.